wholesale use of tio2

In a study published in the journal Toxicology, researchers examined the effects of exposing human colon cancer cell line (HTC116) titanium dioxide food additives in vitro. “In the absence of cytotoxicity, E171 was accumulated in the cells after 24 hours of exposure, increasing granularity and reactive oxygen species, inducing alterations in the molecular pattern of nucleic acids and lipids, and causing nuclei enlargement, DNA damage and tubulin depolymerization,” the scientists wrote. Researchers removed the additive from the culture, then examined the results 48 hours later. They found, “The removal of E171 was unable to revert the alterations found after 24 h of exposure in colon cells. In conclusion, exposure to E171 causes alterations that cannot be reverted after 48 h if E171 is removed from colon cells.”

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In conclusion, the use of food-safe titanium dioxide in manufacturing poses both promises and perils. While it is an effective and affordable whitening agent, there are concerns regarding its potential health risks when consumed in large quantities over a long period of time. To address these concerns, it is important for manufacturers to take steps to ensure the safe use of TiO2 in their products, and for regulatory agencies to establish stronger guidelines and regulations regarding its use.

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